An ontology-driven, case-based clinical decision support model for removable partial denture design
Identifieur interne : 000A66 ( Main/Exploration ); précédent : 000A65; suivant : 000A67An ontology-driven, case-based clinical decision support model for removable partial denture design
Auteurs : Qingxiao Chen [République populaire de Chine] ; Ji Wu [République populaire de Chine] ; Shusen Li [République populaire de Chine] ; Peijun Lyu [République populaire de Chine] ; Yong Wang [République populaire de Chine] ; Miao Li [République populaire de Chine]Source :
- Scientific Reports [ 2045-2322 ] ; 2016.
Abstract
We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient’s oral conditions and denture component parts. During the case-based reasoning process, a cosine similarity algorithm was applied to calculate similarity values between input patients and standard ontology cases. A group of designs from the most similar cases were output as the final results. To evaluate this model, the output designs of RPDs for 104 randomly selected patients were compared with those selected by professionals. An area under the curve of the receiver operating characteristic (AUC-ROC) was created by plotting true-positive rates against the false-positive rate at various threshold settings. The precision at position 5 of the retrieved cases was 0.67 and at the top of the curve it was 0.96, both of which are very high. The mean average of precision (MAP) was 0.61 and the normalized discounted cumulative gain (NDCG) was 0.74 both of which confirmed the efficient performance of our model. All the metrics demonstrated the efficiency of our model. This methodology merits further research development to match clinical applications for designing RPDs. This paper is organized as follows. After the introduction and description of the basis for the paper, the evaluation and results are presented in Section 2. Section 3 provides a discussion of the methodology and results. Section 4 describes the details of the ontology, similarity algorithm, and application.
Url:
DOI: 10.1038/srep27855
PubMed: 27297679
PubMed Central: 4906524
Affiliations:
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<front><div type="abstract" xml:lang="en"><p>We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient’s oral conditions and denture component parts. During the case-based reasoning process, a cosine similarity algorithm was applied to calculate similarity values between input patients and standard ontology cases. A group of designs from the most similar cases were output as the final results. To evaluate this model, the output designs of RPDs for 104 randomly selected patients were compared with those selected by professionals. An area under the curve of the receiver operating characteristic (AUC-ROC) was created by plotting true-positive rates against the false-positive rate at various threshold settings. The precision at position 5 of the retrieved cases was 0.67 and at the top of the curve it was 0.96, both of which are very high. The mean average of precision (MAP) was 0.61 and the normalized discounted cumulative gain (NDCG) was 0.74 both of which confirmed the efficient performance of our model. All the metrics demonstrated the efficiency of our model. This methodology merits further research development to match clinical applications for designing RPDs. This paper is organized as follows. After the introduction and description of the basis for the paper, the evaluation and results are presented in Section 2. Section 3 provides a discussion of the methodology and results. Section 4 describes the details of the ontology, similarity algorithm, and application.</p>
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<affiliations><list><country><li>République populaire de Chine</li>
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</list>
<tree><country name="République populaire de Chine"><noRegion><name sortKey="Chen, Qingxiao" sort="Chen, Qingxiao" uniqKey="Chen Q" first="Qingxiao" last="Chen">Qingxiao Chen</name>
</noRegion>
<name sortKey="Chen, Qingxiao" sort="Chen, Qingxiao" uniqKey="Chen Q" first="Qingxiao" last="Chen">Qingxiao Chen</name>
<name sortKey="Chen, Qingxiao" sort="Chen, Qingxiao" uniqKey="Chen Q" first="Qingxiao" last="Chen">Qingxiao Chen</name>
<name sortKey="Chen, Qingxiao" sort="Chen, Qingxiao" uniqKey="Chen Q" first="Qingxiao" last="Chen">Qingxiao Chen</name>
<name sortKey="Chen, Qingxiao" sort="Chen, Qingxiao" uniqKey="Chen Q" first="Qingxiao" last="Chen">Qingxiao Chen</name>
<name sortKey="Li, Miao" sort="Li, Miao" uniqKey="Li M" first="Miao" last="Li">Miao Li</name>
<name sortKey="Li, Shusen" sort="Li, Shusen" uniqKey="Li S" first="Shusen" last="Li">Shusen Li</name>
<name sortKey="Lyu, Peijun" sort="Lyu, Peijun" uniqKey="Lyu P" first="Peijun" last="Lyu">Peijun Lyu</name>
<name sortKey="Lyu, Peijun" sort="Lyu, Peijun" uniqKey="Lyu P" first="Peijun" last="Lyu">Peijun Lyu</name>
<name sortKey="Lyu, Peijun" sort="Lyu, Peijun" uniqKey="Lyu P" first="Peijun" last="Lyu">Peijun Lyu</name>
<name sortKey="Lyu, Peijun" sort="Lyu, Peijun" uniqKey="Lyu P" first="Peijun" last="Lyu">Peijun Lyu</name>
<name sortKey="Lyu, Peijun" sort="Lyu, Peijun" uniqKey="Lyu P" first="Peijun" last="Lyu">Peijun Lyu</name>
<name sortKey="Wang, Yong" sort="Wang, Yong" uniqKey="Wang Y" first="Yong" last="Wang">Yong Wang</name>
<name sortKey="Wang, Yong" sort="Wang, Yong" uniqKey="Wang Y" first="Yong" last="Wang">Yong Wang</name>
<name sortKey="Wang, Yong" sort="Wang, Yong" uniqKey="Wang Y" first="Yong" last="Wang">Yong Wang</name>
<name sortKey="Wang, Yong" sort="Wang, Yong" uniqKey="Wang Y" first="Yong" last="Wang">Yong Wang</name>
<name sortKey="Wang, Yong" sort="Wang, Yong" uniqKey="Wang Y" first="Yong" last="Wang">Yong Wang</name>
<name sortKey="Wu, Ji" sort="Wu, Ji" uniqKey="Wu J" first="Ji" last="Wu">Ji Wu</name>
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</tree>
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